朱芸欣

Joyce Chu

人的生命有限,但是潛能卻是無限的。我想做、實現的理想太多,深知唯有把握每個當下,才是對自己的人生負責。


e-mail: [email protected]

  Taipei City, Taiwan  

正職工作經歷

研究助理  •  台北醫學大學

六月 2021 - Present

癌症研究:不同分子量PEG修飾在奈米顆粒對anti-PEG model 的老鼠之影響
藥物分布:不同修飾的奈米顆粒在視網膜的分佈

研究助理  •  台灣大學

九月 2020 - 五月 2021

藥物分布:不同修飾的奈米顆粒在視網膜的分佈
壁報: 2020臺灣奈米生醫學會年會暨研討會、
台北醫學大學109學年度師生聯合學術發表會(Combining Mg-Zn-Ca Bulk Metallic Glass with Nanocomposite of Mesoporous Silica for Bone Tissue Engineering)-第二名

研究助理  •  亞東紀念醫院

十月 2017 - 六月 2018

利用westernblot,分析探討在human corneal epithelial
cells, human lens epithelial
cells, Fibroblast 之 不同蛋白的表現
壁報:中華民國眼科醫學會第53次 地方學術研討會 (Upregulating Bcl-xL contributed to cell growth after LED exposure in human corneal epithelial cells
人類角膜上皮細胞表現Bcl-xL有助於受到發光二極體光源照射後之細胞生長)

義工/實習工作經歷

企劃  •  台北靈糧堂

七月 2013 - 十月 2017

活動企劃(夏令營/冬令營)
社區關懷

學歷


2018 - 2020

台北醫學大學

生醫材料暨組織工程研究所 (醫藥工程學類)

2012 - 2016

亞東技術學院 Oriental Institute of Technology

材料與纖維學系(紡織工程學類)

Master Thesis


Combining Mg-Zn-Ca Bulk Metallic Glass with Nanocomposite of Mesoporous Silica for Bone Tissue Engineering




Aims: To demonstrate the osteogenesis in bone healing through the stimulation by degradation product from Mg-Zn-Ca BMG, and OGP released from ex-MSN to attain to bone regeneration.

Results: In vitro study showed that the released metal ions from degradation of Mg-Zn-Ca BMG could promote the cell proliferation and elevate the cells’ migration ability as well as the ALP activity and mineralization. Despite the planned MSN (without OGP) showed little inhibition in cell migration and mineralization, superior results were obtained while treating cells simultaneously with the extracted-MEM and OGP-loaded ex-MSN. This result was contributed by the OGP via enhancing the focal adhesion turnover and promoting the differentiation. Hematological analysis also confirmed the biocompatibility of this BMG/nanocomposite system. In addition, in vivo micro-CT and histological observation revealed that our system could stimulate the osteogenesis and new bone formation around the implant site.

Conclusions: We have integrated Mg-based BMG materials with OGP conjugated ex-MSN to benefit the bone regeneration in both of the in vitro and vivo study. Thus, our system may have a potential to be applied on bone tissue engineering.

Skills


實驗技能


  • 分子生物學實驗
  • Western Blotting
  • PCR Primer Design
  • PCR
  • Plasmid purification
  • DNA cloning
  • Electrophoresis
  • Point mutation
  • Cell Culture
  • Cell experiment
  • Nanoparticles synthesis
  • Nanoparticles design
  • SEM
  • TEM
  • Confocal Microscopy
  • Immunofluorescence
  • Frozen section
  • Animals experiment


文書技能


  • Word
  • PowerPoint
  • Excel
  • Prism


語言


  • Chinese — 母語或雙語
  • English —  中階
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