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4-6 years
6-10 years
10-15 years
More than 15 years
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資料分析師 Data Analyst @Portto 門戶科技| Blocto
2022 ~ 2024
Data Analyst、Data Engineer、Data Scientist、Customer Experience Analyst
Within one month
python
R
MySQL
Employed
Ready to interview
Full-time / Interested in working remotely
4-6 years
臺灣大學
流行病學與預防醫學所 生物統計組
Avatar of the user.
Avatar of the user.
智慧製造全端開發工程師 @聯華電子股份有限公司
2022 ~ Present
AI工程師、機器學習工程師、深度學習工程師、影像演算法工程師、資料科學家、Machine Learning Engineer、Deep Learning Engineer、Data Scientist
Within one month
Python
Qt
Git
Employed
Ready to interview
Full-time / Interested in working remotely
4-6 years
元智大學
工業工程與管理學系所
Avatar of the user.
Avatar of the user.
Past
博士後研究員 @洛桑大學神經發育疾病實驗室
2023 ~ 2023
Data Scientist, Data Analyst, Machine Learning Engineer
Within one month
Data Science
Data Analysis
Machine Learning
Unemployed
Ready to interview
Full-time / Interested in working remotely
4-6 years
洛桑聯邦理工學院(EPFL)
神經科學
Avatar of 李慕全(MuChuan Li).
Avatar of 李慕全(MuChuan Li).
Past
Service Provider @Taron Solutions Limited
2023 ~ 2023
AI工程師、機器學習工程師、電腦視覺工程師、資料科學家、Machine Learning Engineer、Computer Vision Engineer、Data Scientist
Within one month
李慕全(MuChuan Li) 畢業於國立臺北科技大學資工所,研究領域為深度學習、電腦視覺、及影像處理。在學期間致力於應用電腦視覺技術解決交通問題,擁有多項產學合作的專案開發經驗,亦在電腦視覺領域中發表過多篇學術論文,主要研究主題包含物
Machine Learning
Computer Vision
Pytorch/Tensorflow
Unemployed
Ready to interview
Full-time / Interested in working remotely
4-6 years
國立臺北科技大學
資訊工程
Avatar of 宋浩茹 Ellie Sung.
AI工程師、機器學習工程師、深度學習工程師、資料科學家、Machine Learning Engineer、Deep Learning Engineer、Data Scientist
Within one month
宋浩茹 Hao-Ru Sung| [email protected] | LinkedIn | GitHub A s a Research Assistant at Academia Sinica , specializing in Generative AI research and application. With 3 + years of experience in NLP a nd Machine Learning , along with 4+ years in Backend Development . Proficient at translating complex theories into practical applications. Skills Languages: Python, R, SQL, MATLAB, C, C#, JavaScript, Node.js Software & Tools: PyTorch, PyTorch Lightning, Tensorflow, Scikit-Learn, NLTK , GCP, Linux, SQL / NoSQ , Pandas, Hugging Face, Gradio, LangChain, Tensorflow, Keras, FastAPI, OpenCV, Airflow
Python
R
Natural Language Processing (NLP)
Employed
Ready to interview
Full-time / Interested in working remotely
4-6 years
國立政治大學(National Chengchi University)
資訊科學系
Avatar of Chun-Jung Huang.
Avatar of Chun-Jung Huang.
OPC Chief Engineer @TSMC
2020 ~ Present
AI工程師、機器學習工程師、深度學習工程師、資料科學家、Machine Learning Engineer、Deep Learning Engineer、Data Scientist
Within one month
Chun-Jung Huang [email protected] Chiao-Tung University, Ph.D. - Photonics,2015 ~ 2020 Member of The Phi Tau Phi Scholastic Honor Society of the Republic of China. Work Experience TSMC, OPC Chief Engineer (MarPresent) ◆Introduced image anomaly detection techniques to identify and address defects in photomask manufacturing, significantly improving product quality and reducing turnaround time. ◆Managed large-scale data processing tasks, demonstrating expertise in analyzing and handling datasets of hundreds of millions, to bolster model development and optimization. ◆Excelled in distributed computing, optimizing code execution across thousands of systems to
Deep learning with TensorFlow
Translational Research
Clinical Research
Employed
Ready to interview
Full-time / Interested in working remotely
4-6 years
National Chiao-Tung University
Ph.D. - Clinical Engineering
Avatar of 梁賦康 (Foo-Hong, Leong).
Avatar of 梁賦康 (Foo-Hong, Leong).
Product Manager @東元電機股份有限公司 (TECO Electric & Machinery Co. Ltd.)
2023 ~ 2023
Data Scientist, Data Analyst, Machine Learning Engineer
Within one month
梁賦康 (Foo-Hong, Leong) Taoyuan City, Taiwan Email: [email protected] Tel:Skills • Languages: Python • DataBases: MySQL, SQLite • Infrastructure tools: Github • Machine learning libraries: TensorFlow, Keras, and Scikit-learn • Data visualization tools: Power BI, Seaborn and Matplotlib • Deployment: Streamlit Summary I have been working in Motor Manufacturing Industry for 8 years. My first programming was going to my Bachelor's degree, C++ was the first program I learned. Then I started to learn Python in 2018 at TEDU and my first project was the Stock Trend Prediction by CNN. I kept
Python
Power BI
Data Analytics
Employed
Ready to interview
Full-time / Interested in working remotely
6-10 years
國立成功大學 National Cheng Kung University
Mechanical Engineering
Avatar of 陳奕妤.
Avatar of 陳奕妤.
Past
Senior Data Analyst @趨勢科技
2022 ~ Present
Data Scientist, Data Analyst, Machine Learning Engineer
Within one month
customers by using statistical methods and machine learning methods. Developing automation regular reports, maintaining SQL store procedures, Tableau dashboards and Power BI dashboards. Cooperated with cross-functional team (Product, Marketing, Platform, PM, IT, Sales) to provide timely and accuracy business insight analysis. Developing automated web crawler on MMA website to collect ETF, fund, bond information. Skill : Microsoft SQL Server · Microsoft Power BI · Data Cubes · R · Python · Tableau · Web Crawling · machine learning · IMPALA · HIVE · Git · Docker Data Analyst • Catchplay AprOct 2020 Indonesia OTT customer profile analysis - Collecting, analyzing and evaluating data and campaign performa...
python
R
SQL
Unemployed
Ready to interview
Full-time / Interested in working remotely
4-6 years
輔仁大學 Fu Jen Catholic University
統計資訊學系
Avatar of Nelson Chen.
Avatar of Nelson Chen.
Senior engineer @Chicony Electronics Co, Ltd.
2018 ~ Present
全端工程師、後端工程師、前端工程師、軟體專案主管、AI工程師、機器學習工程師、深度學習工程師、資料科學家、Machine Learning Engineer、Deep Learning Engineer、Data Scientist
Within one month
Nelson Chen Senior engineer Dedicated Software Engineer with 6+ Years of Experience Senior software engineer specializing in web page development and deep learning. Proficient with machine learning technologies, such as TensorFlow, Numpy, etc. Experience Senior engineer • Chicony Electronics Co, Ltd. .Build an Auto-Encoder AI model for defective detection. .Build an object detection model for detecting car types. .Developed a Front-End and Back-End website for data analysis. .Manage the production process and make it automated production. NovPresent Software engineer • Teco image systems co. ltd .Developed and maintained MFP driver
Python
C
C++
Employed
Ready to interview
Full-time / Interested in working remotely
6-10 years
National Taiwan Ocean University
Computer science and engineering
Avatar of Vu Nguyen Ngoc Quang.
Avatar of Vu Nguyen Ngoc Quang.
Past
Mobile App Developer @Apple Inc.
2014 ~ Present
Lead Infrastructure Engineer
Within two months
party APIs into existing mobile applications. Created user interfaces for mobile apps based on design specifications. Optimized mobile applications for performance and scalability. Developed databases that supported Web applications and Web sites. Developed system interaction and sequence diagrams. Big Data Engineer • Freelancer JuneJuly 2023 Built machine learning models using TensorFlow and Scikit-Learn libraries for predictive analysis of customer behavior. Designed and implemented a scalable data warehouse architecture using Apache Cassandra, PostgresDB, and Redis. Optimized database performance by tuning queries in SQL Server, Oracle and PostgreSQL databases. Implemented efficient data processing algorithms
Machine learning
Virtualization Technologies
Pandas Python
Unemployed
Ready to interview
Full-time / Interested in working remotely
6-10 years

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Adaptability
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Within six months
Python Engineer | Machine Learning Engineer | Cloud Solutions Architect for AWS
Logo of International Integrated Systems, Inc.(IISI).
International Integrated Systems, Inc.(IISI)
2022 ~ Present
New Taipei, Banqiao District, New Taipei City, Taiwan
Professional Background
Current status
Employed
Job Search Progress
Professions
Machine Learning Engineer, Python Developer
Fields of Employment
Work experience
1-2 years work experience (Less than 1 year relevant)
Management
None
Skills
Python
Machine Learning
Deep Learning
AWS
chatbot
Host Management
Languages
Chinese
Native or Bilingual
English
Intermediate
Job search preferences
Positions
AI工程師、機器學習工程師、深度學習工程師、資料科學家、Machine Learning Engineer、Deep Learning Engineer、Data Scientist
Job types
Full-time
Locations
Taipei, Taiwan, Taipei City, Taiwan, Taoyuán, 台灣, Hsinchu City, 台灣, Hsinchu County, 台灣, Hsinchu, 新竹市台灣
Remote
Interested in working remotely
Freelance
No
Educations
School
National Chung Hsing University
Major
Graduate Institute of Biotechnology
Print
Use0hzx0oye3ersbch4l

洪瑋辰 Esther Hung

Machine Learning Engineer | Python Engineer | Cloud Solutions Architect for AWS

Studied Machine Learning in an AI Lab


[email protected] 
(+886) 937294582


Skills


  • Python
    • Web crawler (selenium and requests)
    • Organize web crawler results (beautifulsoup)
    • Data ETL
    • Simple web (flask)
    • Simple LineBot for setting notifications (Django and linebot)
    • Create numerous AWS CloudWatch alarms (boto3)
    • Auto run numerous Weka models and organize results to tables
    • Auto send data, get results, and organize results to tables for Pse-in-one 2.0
    • Switch amino acid to representing values based on AAindex rules
    • Rasa actions 
    • Create independent environment (venv)
    • Test chatbot NLU model performance (psycopg2, pandas, requests)
    • Change chatbot old format to new format
    • Remote reboot host while ssh does not work (SimpleHTTPServer)
  • Machine Learning
    • Do feature encoding for data with related informations
    • Build prediction models with LibSVM, Weka, MLP, CNN, RNN, LSTM
    • Keras and Tensorflow for building models
    • Do independent tests, cross validations, and case study for models
    • Evaluate models with ACC, AUC, MCC, F1, Sensitivity (Sn), and Specificity (Sp)
    • Modify number of iterations (epochs) and batch size for optimizing models
    • Set early stopping to avoid overtraining
    • Modify pooling size, learning rate, kernel or filter size, and dropout rate for optimizing models
    • Modify activation functions, optimizers, and loss functions for optimizing models
    • Modify number of hidden layers and number of activation units for optimizing models
    • Modify LibSVM code for adding additional evaluation metrics (C)
    • Scikit-learn for drawing ROC curve and calculate
    • Rasa framework for chatbot
  • AWS
    • IAM (create users for customer's consulters, create roles for aws services, and create policies for users or roles based on least privilege)
    • VPC (create subnets, set route table, set NAT gateway, create endpoint, and create Client VPN)
    • EC2 (write user data, set security group, add hosts, install and set cloudwatch agent, set auto start and stop, change a hostname, change a password, add to an AD, create images, set lifecycle manager, set auto backup for Microsoft SQL Server database, and set related setting for connection)
    • S3 (create buckets, set bucket policies, and set lifecycle managements)
    • ELB (set listeners, edit listener rules, target groups, and set security group)
    • ECS (set task definitions, create clusters, set services, connect load balancers, and set auto scaling)
    • CloudWatch (create dashboards and set alarms)
    • QuickSight (design simple dashbroads, create datasources, and design datasets)
    • Lambda (set Client VPN whitelist, auto refresh QuickSight, and create numerous CloudWatch alarms)
    • Systems Manager (set auto start and stop EC2, set auto reboot EC2, and reset EC2 password for forgetting password)
    • WorkSpaces (create workspaces, create images, create bundlers, and set IP access controls)
    • SDK (AWSCLI, AWSPowerShell, and boto3)
    • WAF (basic setting and modify AWS-managed rules)
    • Route 53 (basic setting and manage forwarding rules)
    • CloudFront (basic setting and set security header)
  • Host Management
    • Prometheus and Grafana for monitor (CPU, Memory, GPU, Disk Write/Read, Disk available bytes, Service status)
    • Node-RED for scheduler
    • Nginx for reverse proxy
    • Docker for runtime environment and database
    • Openvpn server management
    • Account management for hosts and applications
    • Database management for PostgreSQL and MongoDB
    • Write some scripts to backup system and application logs
    • Update OS to latest version and make sure services are all right (Ubuntu)
    • Integrate the old version framework and the latest version OS (Ubuntu)
    • Reinstall the latest version OS and build product environment (Ubuntu)
    • Fix weak points from source code analysis and vulnerability assessment reports
    • Deploy new version product to test and production environment
  • Windows PowerShell (AWS)
    • Write a script to connect to EC2 in a private subnet for customers
    • Write a script to download files from S3 for customers
    • Write a script to upload backup files to S3 and delete local backup files for customers
  • Linux Shell (AWS)
    • Write a script to download files from S3 for customers
    • Write a script to upload backup files to S3 and delete local backup files for customers

Work Experience

Engineer (Information Technology)
International Integrated Systems, Inc.(IISI)

November 2022 ~ June 2023

  • Operation and maintenance for chatbot product
  • Optimize chatbot product
  • Host management (Ubuntu)
  • Database management (PostgreSQL and MongoDB)
  • Openvpn server management
  • Fix weak points from source code analysis and vulnerability assessment reports
  • Assist project manager in satisfying customer's requirement
  • Assist project manager in solving customer's problems
  • Support project manager in technical side
  • Deploy new version product to test and production environment
  • Research monitor and alert
  • Research product CI/CD

Project Engineer (Information Technology)
CHUAN KAI INTERNATIONAL CO.,LTD (CKmates)

June 2021 ~ July 2022

  • Assist the customer in designing, creating, and setting a cloud environment for obtaining PCI DSS Certification
  • Assist the customer in designing, creating, and setting a cloud environment for SAP B1 and HANA Database
  • Assist the customer in designing, creating, and setting a cloud environment for SAP B1 and Microsoft SQL Server Database
  • Assist customers in solving problems
  • Write technical documents for customers and colleagues
  • Be the contact person for projects
  • Organize tables of AWS cloud environment informations for customers and colleagues
  • Research and discuss with colleagues for cloud architecture

Projects (IISI)


Chatbot Product

  • Customization training data
  • Customization functions
  • Management Platform (switch bot status, produce reports,etc)
  • Bot (Q&A, Multi-turn dialogue, element, button)


Optimize Chatbot Product

  • Research the latest version framework
  • Research different component performance
  • Redesign product framework
  • Research automation
  • Research monitor and alert

Projects (CKmates)


Payment Flow Cloud Architecture

  • ECS and EC2 for deploying server
  • Route 53 and ELB for allocating traffic
  • WAF for API and DB security
  • CloudFront for security header
  • CloudWatch for monitoring
  • IAM for necessary permissions
  • VPC for networking



SAP B1 + HANA Cloud Architecture

  • EC2 for deploying HANA DB
  • WorkSpaces for B1 client connection
  • Nginx for web connection
  • S3 for storaging backup and software
  • Lambda for client vpn whitelist
  • CloudWatch for monitoring
  • IAM for necessary permissions
  • VPC for networking 


SAP B1 + SQL Server Cloud Architecture

  • EC2 for deploying SQL Server DB 
  • WorkSpaces for B1 client connection 
  • Nginx for web connection 
  • S3 for storaging backup and software 
  • CloudWatch for monitoring 
  • IAM for necessary permissions 
  • VPC for networking 

Thesis

Building a prediction model for the binding of major histocompatibility complex proteins and peptides 

Projects 01 00@2x

Major histocompatibility complex (MHC) is a set of genes about acquired immune system in vertebrates. The function of MHC is mainly to help vertebrates recognize foreign molecules. There are a lot of issues about MHC in immunity and medical science, such as the susceptibility of autoimmune diseases, adverse drug reaction, and organ transplant. In order to lower the experiments cost, researchers built the prediction model for MHC binding. We built a prediction model for the binding of MHC class I proteins and peptides, named EsMHC, based on machine learning (LibSVM, Weka, and MLP) and a new method of building models: comprehensive strategy. Comprehensive strategy in EsMHC is a strategy to integrate two methods of building models (allele-specific method and pan-allele method) for balancing of strengths and weakness. Moreover, we added MHC Allele encoding developed by ourselves to feature encoding for improving prediction speed and performance. Overall, our model has great prediction performance (AUC = 0.91, ACC = 0.89, F1 = 0.91, and MCC = 0.65). The evaluation metrics of our model are almost higher than other models.

Certifications

AWS Certified Cloud Practitioner

Issued by Amazon Web Services Training and Certification on July 21, 2021

Expires on October 19, 2026

https://www.credly.com/badges/8b96ed58-2ac9-498f-b4ce-667d5d88997d/public_url

AWS Certified Machine Learning – Specialty

Issued by Amazon Web Services Training and Certification on October 03, 2021

Expires on October 03, 2024

https://www.credly.com/badges/9f14f5aa-b46a-4c45-ad3c-fdaf11d8d182/public_url

AWS Certified Solutions Architect – Associate

Issued by Amazon Web Services Training and Certification on November 27, 2021

Expires on November 27, 2024

https://www.credly.com/badges/893a1b78-cbdd-4c33-b254-eeab91d95d3a/public_url

AWS Certified Developer – Associate

Issued by Amazon Web Services Training and Certification on October 19, 2023

Expires on October 19, 2026

https://www.credly.com/badges/1a769f99-b2e6-4a9d-9ba1-019193d0e4bd/public_url

Education

National Chung Hsing University, Master's Degree, Graduate Institute of Biotechnology, 2017 ~ 2020

National Chiayi University, Bachelor's Degree, Department of Plant Medicine, 2013 ~ 2017

Resume
Profile
Use0hzx0oye3ersbch4l

洪瑋辰 Esther Hung

Machine Learning Engineer | Python Engineer | Cloud Solutions Architect for AWS

Studied Machine Learning in an AI Lab


[email protected] 
(+886) 937294582


Skills


  • Python
    • Web crawler (selenium and requests)
    • Organize web crawler results (beautifulsoup)
    • Data ETL
    • Simple web (flask)
    • Simple LineBot for setting notifications (Django and linebot)
    • Create numerous AWS CloudWatch alarms (boto3)
    • Auto run numerous Weka models and organize results to tables
    • Auto send data, get results, and organize results to tables for Pse-in-one 2.0
    • Switch amino acid to representing values based on AAindex rules
    • Rasa actions 
    • Create independent environment (venv)
    • Test chatbot NLU model performance (psycopg2, pandas, requests)
    • Change chatbot old format to new format
    • Remote reboot host while ssh does not work (SimpleHTTPServer)
  • Machine Learning
    • Do feature encoding for data with related informations
    • Build prediction models with LibSVM, Weka, MLP, CNN, RNN, LSTM
    • Keras and Tensorflow for building models
    • Do independent tests, cross validations, and case study for models
    • Evaluate models with ACC, AUC, MCC, F1, Sensitivity (Sn), and Specificity (Sp)
    • Modify number of iterations (epochs) and batch size for optimizing models
    • Set early stopping to avoid overtraining
    • Modify pooling size, learning rate, kernel or filter size, and dropout rate for optimizing models
    • Modify activation functions, optimizers, and loss functions for optimizing models
    • Modify number of hidden layers and number of activation units for optimizing models
    • Modify LibSVM code for adding additional evaluation metrics (C)
    • Scikit-learn for drawing ROC curve and calculate
    • Rasa framework for chatbot
  • AWS
    • IAM (create users for customer's consulters, create roles for aws services, and create policies for users or roles based on least privilege)
    • VPC (create subnets, set route table, set NAT gateway, create endpoint, and create Client VPN)
    • EC2 (write user data, set security group, add hosts, install and set cloudwatch agent, set auto start and stop, change a hostname, change a password, add to an AD, create images, set lifecycle manager, set auto backup for Microsoft SQL Server database, and set related setting for connection)
    • S3 (create buckets, set bucket policies, and set lifecycle managements)
    • ELB (set listeners, edit listener rules, target groups, and set security group)
    • ECS (set task definitions, create clusters, set services, connect load balancers, and set auto scaling)
    • CloudWatch (create dashboards and set alarms)
    • QuickSight (design simple dashbroads, create datasources, and design datasets)
    • Lambda (set Client VPN whitelist, auto refresh QuickSight, and create numerous CloudWatch alarms)
    • Systems Manager (set auto start and stop EC2, set auto reboot EC2, and reset EC2 password for forgetting password)
    • WorkSpaces (create workspaces, create images, create bundlers, and set IP access controls)
    • SDK (AWSCLI, AWSPowerShell, and boto3)
    • WAF (basic setting and modify AWS-managed rules)
    • Route 53 (basic setting and manage forwarding rules)
    • CloudFront (basic setting and set security header)
  • Host Management
    • Prometheus and Grafana for monitor (CPU, Memory, GPU, Disk Write/Read, Disk available bytes, Service status)
    • Node-RED for scheduler
    • Nginx for reverse proxy
    • Docker for runtime environment and database
    • Openvpn server management
    • Account management for hosts and applications
    • Database management for PostgreSQL and MongoDB
    • Write some scripts to backup system and application logs
    • Update OS to latest version and make sure services are all right (Ubuntu)
    • Integrate the old version framework and the latest version OS (Ubuntu)
    • Reinstall the latest version OS and build product environment (Ubuntu)
    • Fix weak points from source code analysis and vulnerability assessment reports
    • Deploy new version product to test and production environment
  • Windows PowerShell (AWS)
    • Write a script to connect to EC2 in a private subnet for customers
    • Write a script to download files from S3 for customers
    • Write a script to upload backup files to S3 and delete local backup files for customers
  • Linux Shell (AWS)
    • Write a script to download files from S3 for customers
    • Write a script to upload backup files to S3 and delete local backup files for customers

Work Experience

Engineer (Information Technology)
International Integrated Systems, Inc.(IISI)

November 2022 ~ June 2023

  • Operation and maintenance for chatbot product
  • Optimize chatbot product
  • Host management (Ubuntu)
  • Database management (PostgreSQL and MongoDB)
  • Openvpn server management
  • Fix weak points from source code analysis and vulnerability assessment reports
  • Assist project manager in satisfying customer's requirement
  • Assist project manager in solving customer's problems
  • Support project manager in technical side
  • Deploy new version product to test and production environment
  • Research monitor and alert
  • Research product CI/CD

Project Engineer (Information Technology)
CHUAN KAI INTERNATIONAL CO.,LTD (CKmates)

June 2021 ~ July 2022

  • Assist the customer in designing, creating, and setting a cloud environment for obtaining PCI DSS Certification
  • Assist the customer in designing, creating, and setting a cloud environment for SAP B1 and HANA Database
  • Assist the customer in designing, creating, and setting a cloud environment for SAP B1 and Microsoft SQL Server Database
  • Assist customers in solving problems
  • Write technical documents for customers and colleagues
  • Be the contact person for projects
  • Organize tables of AWS cloud environment informations for customers and colleagues
  • Research and discuss with colleagues for cloud architecture

Projects (IISI)


Chatbot Product

  • Customization training data
  • Customization functions
  • Management Platform (switch bot status, produce reports,etc)
  • Bot (Q&A, Multi-turn dialogue, element, button)


Optimize Chatbot Product

  • Research the latest version framework
  • Research different component performance
  • Redesign product framework
  • Research automation
  • Research monitor and alert

Projects (CKmates)


Payment Flow Cloud Architecture

  • ECS and EC2 for deploying server
  • Route 53 and ELB for allocating traffic
  • WAF for API and DB security
  • CloudFront for security header
  • CloudWatch for monitoring
  • IAM for necessary permissions
  • VPC for networking



SAP B1 + HANA Cloud Architecture

  • EC2 for deploying HANA DB
  • WorkSpaces for B1 client connection
  • Nginx for web connection
  • S3 for storaging backup and software
  • Lambda for client vpn whitelist
  • CloudWatch for monitoring
  • IAM for necessary permissions
  • VPC for networking 


SAP B1 + SQL Server Cloud Architecture

  • EC2 for deploying SQL Server DB 
  • WorkSpaces for B1 client connection 
  • Nginx for web connection 
  • S3 for storaging backup and software 
  • CloudWatch for monitoring 
  • IAM for necessary permissions 
  • VPC for networking 

Thesis

Building a prediction model for the binding of major histocompatibility complex proteins and peptides 

Projects 01 00@2x

Major histocompatibility complex (MHC) is a set of genes about acquired immune system in vertebrates. The function of MHC is mainly to help vertebrates recognize foreign molecules. There are a lot of issues about MHC in immunity and medical science, such as the susceptibility of autoimmune diseases, adverse drug reaction, and organ transplant. In order to lower the experiments cost, researchers built the prediction model for MHC binding. We built a prediction model for the binding of MHC class I proteins and peptides, named EsMHC, based on machine learning (LibSVM, Weka, and MLP) and a new method of building models: comprehensive strategy. Comprehensive strategy in EsMHC is a strategy to integrate two methods of building models (allele-specific method and pan-allele method) for balancing of strengths and weakness. Moreover, we added MHC Allele encoding developed by ourselves to feature encoding for improving prediction speed and performance. Overall, our model has great prediction performance (AUC = 0.91, ACC = 0.89, F1 = 0.91, and MCC = 0.65). The evaluation metrics of our model are almost higher than other models.

Certifications

AWS Certified Cloud Practitioner

Issued by Amazon Web Services Training and Certification on July 21, 2021

Expires on October 19, 2026

https://www.credly.com/badges/8b96ed58-2ac9-498f-b4ce-667d5d88997d/public_url

AWS Certified Machine Learning – Specialty

Issued by Amazon Web Services Training and Certification on October 03, 2021

Expires on October 03, 2024

https://www.credly.com/badges/9f14f5aa-b46a-4c45-ad3c-fdaf11d8d182/public_url

AWS Certified Solutions Architect – Associate

Issued by Amazon Web Services Training and Certification on November 27, 2021

Expires on November 27, 2024

https://www.credly.com/badges/893a1b78-cbdd-4c33-b254-eeab91d95d3a/public_url

AWS Certified Developer – Associate

Issued by Amazon Web Services Training and Certification on October 19, 2023

Expires on October 19, 2026

https://www.credly.com/badges/1a769f99-b2e6-4a9d-9ba1-019193d0e4bd/public_url

Education

National Chung Hsing University, Master's Degree, Graduate Institute of Biotechnology, 2017 ~ 2020

National Chiayi University, Bachelor's Degree, Department of Plant Medicine, 2013 ~ 2017