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Yishul Wei

⁄ Researcher ⁄ Neuroscientist ⁄ Data Scientist ⁄

Netherlands Institute for Neuroscience
Meibergdreef 47
1105 BA, Amsterdam, Netherlands

[email protected]


  About Me

A passionate brain and behavior researcher with backgrounds in mathematical and computational sciences.

Versed in programming, scientific computing, research design and data analysis.

Professional Specializations

  • Cognitive science
  • Quantitative brain imaging
  • Medical physics
  • Psychophysiology
  • Temporal & spatial signal processing
  • Research methodology, design of (quasi-)experiments & statistics

Other Skills

  • Machine learning
  • Natural language processing
  • Information retrieval
  • Database systems
  • Linked data
  • Web programming

  Research Summary

The main focus of my current research is on  sleep and its relation to emotion, cognition and consciousness in both healthy and sleep-disordered humans. Sleep takes up one-third of a person's life, and good-quality sleep is vital for optimal daily functioning and well-being — a fact that is, unfortunately, often not appreciated. My collaborators and I have taken multiple approaches (lab experiments, field experiments, ambulatory monitoring and experience sampling) and applied a wide range of techniques (web-based questionnaires, psychological tests, wearable technology, brain imaging and computational modeling) in our investigations to thoroughly examine the mechanisms and functional impacts of good and bad sleep.

  Scientific Publications

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NEW! Insomnia disorder subtypes derived from life history and traits of affect and personality

T.F. Blanken, J.S. Benjamins, D. Borsboom, J.K. Vermunt, C. Paquola, J. Ramautar, K. Dekker, D. Stoffers, R. Wassing, Y. Wei, E.J.W. Van Someren

The Lancet Psychiatry (2019) doi:10.1016/S2215-0366(18)30464-4
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EEG microstates indicate heightened somatic awareness in insomnia: toward objective assessment of subjective mental content

Y. Wei, J.R. Ramautar, M.A. Colombo, B.H.W. te Lindert, E.J.W. Van Someren

Frontiers in Psychiatry (2018) doi:10.3389/fpsyt.2018.00395

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Insomnia really hurts: effect of a bad nights sleep on pain increases with insomnia severity

Y. Wei Y, T.F. Blanken, E.J.W. Van Someren

Frontiers in Psychiatry (2018) doi:10.3389/fpsyt.2018.00377
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Sustained effects of prior red light on pupil diameter and vigilance during subsequent darkness

W.P. van der Meijden, B.H.W. te Lindert, J.R. Ramautar, Y. Wei, J.E. Coppens, M. Kamermans, C. Cajochen, P. Bourgin, E.J.W. Van Someren

Proceedings of the Royal Society B (2018) doi:10.1098/rspb.2018.0989
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Sleep stage transition dynamics reveal specific stage 2 vulnerability in insomnia

Y. Wei, M.A. Colombo, J.R. Ramautar, T.F. Blanken, Y.D. van der Werf, K. Spiegelhalder, B. Feige, D. Riemann, E.J.W. Van Someren

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I keep a close watch on this heart of mine: increased interoception in insomnia

Y. Wei, J.R. Ramautar, M.A. Colombo, D. Stoffers, G. Gomez-Herrero, W.P. van der Meijden, B.H.W. te Lindert, Y.D. van der Werf, E.J.W. Van Someren

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More severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG

M.A. Colombo, Y. Wei, J.R. Ramautar, K. Linkenkaer-Hansen, E. Tagliazucchi, E.J.W. Van Someren

Frontiers in Physiology (2016) doi:10.3389/fphys.2016.00576
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Wake high-density electroencephalographic spatiospectral signatures of insomnia

M.A. Colombo, J.R. Ramautar, Y. Wei, G. Gomez-Herrero, D. Stoffers, R. Wassing, J.S. Benjamins, E. Tagliazucchi, Y.D. van der Werf, C. Cajochen, E.J.W. Van Someren

  Software

CardyLine (beta): MATLAB toolbox enabling one-liner heart rate variability analysis directly from electrocardiogram (ECG).

Program DFluC: MATLAB program for Detrended Fluctuation Analysis.


I am the de facto maintainer of meegpipe, a large library of MATLAB tools for handling massive physiological datasets and temporal/spatial preprocessing.

  Past Presentations

Invited Talks

  • 10/2017 > 25th Annual Meeting of the German Sleep Society
  • 12/2016 > 4th European Insomnia Network Meeting

Poster Presentations

  • 09/2018 > 24th Congress of the European Sleep Research Society
  • 08/2017 > 13th International Conference for Cognitive Neuroscience
  • 09/2016 > 23rd Congress of the European Sleep Research Society
  • 10/2015 > 7th Quadrennial Congress of the World Sleep Federation

  Past Teaching

Teaching assistant @ Paul G. Allen School of Computer Science & Engineering, University of Washington

  • CSE 431: Introduction to the Theory of Computation (Spring '14)
    Turing machines, the Church–Turing thesis, nondeterminism, computability, recursion theory, complexity theory, P vs. NP, NP-completeness, PSPACE, time and space hierarchy theorems
  • CSE 344: Introduction to Data Management (Winter '14)
    Relational databases, RDBMS, SQL, relational algebra, relational logic, Datalog, XML, DTD, RDF, XPath, XQuery, database design, transactions, parallel database systems, MapReduce, Hadoop, data programming on Amazon EC2
  • CSE 473: Introduction to Artificial Intelligence (Autumn '13)
    Classical search, heuristic search, games, knowledge representation, logical reasoning, Markov decision processes, Q-learning, Bayesian networks, decision trees, support vector machines, neural networks

  Honors and Awards

FENS and IBRO-PERC Stipend 2019
Travel grants from the European Sleep Research Society
NeuroTime: Erasmus Mundus Joint Doctorate "Neural processing of time" studentship [declined]
1st Place in Quantiacs LLC's Kickoff Contest; 3rd Place in the Futures Contest
Undergraduate Research Experience & Knowledge Award (UREKA) from Science Foundation Ireland
Scholarships from the Ministry of Education, Taiwan
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"Complex Rhythm Sustaining Complex Life"

Honorable Mention in 2018 Art of Neuroscience competition

  Grant Support

BIAL Foundation Grant 190/16: "Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep"

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