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Recommended Recommended: Pentium 2 GHz or . Optional: If using VMWare see [VMware Requirements]{} ** Binary downloads** `[Windows installers: Win32, x86, x64, ia64 (some features not supported on ia64)]{}` [^1]: [ [^2]: [ [^3]: See [^4]: Note, that the product images are Windows Server 2008 images which are distributed by Microsoft, therefore we are not liable for any damages arising from the use of them. Synthesis and binding properties of D- and L-lysine derivatives of 2- and 3-thienylalanine. The effects of the D- and L-enantiomers of five L-amino acids and their N-methyl derivatives have been investigated for their binding affinities at the phenylalanine binding sites of rat and human GABA-benzodiazepine receptors. The D-enantiomers of the N-methyl derivatives of thiophenealanine (D-l-THAA and D-l-THPA), 3- and 4-thienylalanine (D-3-THAA and D-4-THAA) and 5-hydroxy-l-THAA are reported for the first time. The binding affinities for rat brain benzodiazepine receptors were found to be in the order of D-4-THAA greater than D-5-THAA greater than D-l-THAA greater than D-3-THAA greater than D-l-THPA greater than D-l-THAA greater than D-THPA. The binding affinities for human gamma 2-containing GABA receptors were similar to the values obtained with rat brain receptors. The L-enantiomers of 4-THAA and 5-THAA were studied only in order to compare with previous results. With rat brain receptors the binding affinities of the L-enantiomers were found to be always lower than those of their D-enantiomers, the largest difference being observed for the N-methyl derivatives of 4-THAA and 5-THAA. At the gamma 2-subunit of

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