A former pharmaceutical industry professional, Michele Niklaus served as a senior sales consultant with Glaxo SmithKline Pharmaceuticals from 1997 to 2001 and an executive sales consultant with Novartis Pharmaceuticals from 2001 to 2008. Michele Niklaus also founded and operated the medical supplies provider and mastectomy boutique Saving Grace in Pikeville, Kentucky. Ms. Niklaus also has a history of involvement in the charitable nonprofit sector. From 2018 to 2019, she served as an events coordinator and assistant to the vice president of development with Junior Achievement of Central Ohio. Michele Niklaus currently volunteers with both the Columbus Catholic Women's Conference (CCWC) and Mommies Matter. Performing a range of roles with CCWC since 2011, she has made significant contributions to the largest annual Catholic Women's Conference in the United States. Her work with Mommies Matter includes hosting baby showers for single expectant mothers in crisis. She also assists Mommies Matter with fundraising and community outreach efforts.