The best phone number to call American Airlines, along with strategies for cutting through phone lines and reaching an agent right away, are listed below. Because 183,324 users, including you, used this phone number in the previous 18 months and provided feedback, it is American Airlines' Best Phone Number. The customer support department that responds to calls at 1-800-548-3192 frequently handles issues like Trouble With a Flight, Cancelled Flight, Flight Enquiry, Update Reservation, Discover Itinerary, and other customer service concerns. Customers claim that the 24-hour, seven-day American Airlines call centre is staffed by people from Dallas, Tuscon, North Carolina, India, Mexico, Ireland, Canada, and Japan.